Arsenal and Everton face challenging tests on their return to the Europa League following Friday’s group stage draw in Monaco.
Arsenal were drawn to play Belarus’ BATE Borisov, Cologne of Germany and Serbia’s Red Star Belgrade in Group H.
Everton will play France’s Lyon – hosts of this season’s final – Italy’s Atalanta and Apollon Limassol of Cyprus in Group E.
Both English sides face difficult tasks to advance to the knockout stages when the group phase begins on September 14.
The Gunners had advanced to the knockout stages of the Champions League but lost in the first knock-out round in the last seven seasons and failed to qualify for the tournament through the Premier League in 2016-17.
Everton, who completed their play-off victory over Hajduk Split of Croatia on Thursday, are in Europe for the first time since 2009-10.
Manchester United won the trophy in May to qualify for the Champions League.
United and France midfielder Paul Pogba was named Europa League Player of the Season for 2016-17, ahead of team-mates Zlatan Ibrahimovic and Henrikh Mkhitaryan.
The 48-team draw for this season’s competition included Sweden’s Ostersund, managed by Englishman Graham Potter.
Ostersund will play Spain’s Athletic Bilbao, Germany’s Hertha Berlin and Zorya Luhansk of Ukraine in Group J.