Mnangagwa last week formally recognised Khupe as the official leader of the opposition after the former deputy prime minister sneaked back into Parliament under controversial circumstances.
“I don’t have time for Khupe and Douglas Mwonzora (interim MDC-T secretary-general),” Chamisa said.
“I know they are simply playing a script handed to them by Zanu-PF, enforced by captured institutions.
“They are going nowhere. In fact, they are history. People always settle political disputes.”
Khupe is using a Supreme Court ruling that said she was the legitimate interim leader of the MDC-T after she was elbowed out in the battle to succeed the late Morgan Tsvangirai by Chamisa.
The MDC Alliance, however, insists that it broke ranks with Khupe before the 2018 elections and she has no right to take over legislators and councillors of a party that defeated her in the polls.